Live Webcast: High Throughput in the LC-MS/MS Laboratory
www.chromatographyonline.com/highthroughput - October 24, 2008
November 19, 2008
If SPE, LLE and PPT are acronyms in your daily vocabulary, this is the
webcast for you. You know that ineffective sample extraction can result
in bad data as matrix components suppress or enhance ionization. You
know that sample preparation is a common bottleneck in high volume
LC-MS/MS laboratories.
LC-MS/MS systems continue to attain new levels of sensitivity and detection
allowing for better analysis. Many expected the issue of sample
preparation to go away with the higher sensitive mass spectrometry
systems. This, however, has not been the case. Eliminating ion suppression
(or ion enhancement) still requires removal of the matrix components
prior to MS-MS analysis.
The traditional options for sample preparation include Solid Phase Extraction,
Protein Precipitation or Liquid Liquid Extraction. In the last 10 years,
an online sample extraction technique using turbulent fl ow chromatography
has provided a way to minimize many of the drawbacks of traditional
methods. In this webcast the advantages and disadvantages of these
methods will be compared to a more recent solution utilizing turbulent fl ow
chromatography.
To join go to www.chromatographyonline.com/highthroughput
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