Eliminating Sample Preparation and Speeding Analysis in Discovery and Development
With the industry's widespread use of high throughput screening assays, bottlenecks in the drug discovery and development process have shifted from sample generation to sample analysis. To solve this problem, various liquid chromatography-mass spectrometry (LC-MS/MS) techniques have been introduced to speed sample analysis. But rather than improving the process, the use of standard LC-MS/MS techniques has simply pushed the bottleneck to the sample preparation process.
Thermo Fisher Scientific has developed a solution that vastly shortens - even eliminates - the time needed for sample preparation. Our unique systems save time by eliminating the need for lengthy preparation steps, such as protein precipitation, liquid/liquid extraction, or solid-phase extraction. Instead, you directly inject plasma, urine, or other biological matrices onto the system. Beyond the benefits of performing online sample preparation, our systems can be multiplexed to further speed analysis - up to four times the throughput of a conventional LC-MS/MS system.
Thermo Scientific delivers the most practical, selective, rapid, and cost-effective sample preparation solutions on the market.
Suitable for a range of applications, including bioanalysis, biomarkers, proteomics, metabolite enrichment, our solutions deliver:
- Direct injection of biological fluids
- Four times the throughput of MS
- Enhanced sensitivity and selectivity
- Reduced ion suppression
- Minimal sample preparation